天津招聘

Title: Group leader - bioanalytics
Location: Chengdu, Sichuan
Job Category: Research and development
Employee Status: Full-time
Position: 1

Huiyu Research Institute is seeking a highly motivated and innovative protein analyst/
protein chemist to join its team of experienced drug hunters to invent, identify and
develop large biologic molecules for therapeutic intervention. The successful candidate
will have proven critical thinking skills, as evidenced through academic and patent
publications, and will report to the director of Antibody Discovery Department to be
part of a cross-functional team that collaboratively develops therapeutic monoclonal
antibodies and recombinant proteins. He or she will be responsible for the analysis and
characterization of generated recombinant proteins, including antibodies. The
candidate will work closely with the project teams, as well as external CROs, in a highly
collaborative and fast-paced environment. The successful candidate should be a selfmotivated
individual with demonstrated experience in protein analytics and
characterization and have contributed to the development of therapeutic Biologics
molecules.

Responsibilities
? Responsible for the development and optimization of analytical methods for
protein characterization.
? Conduct the characterization and protein analysis of multiple recombinant
proteins, including monoclonal antibodies.
Carry out or oversee mAb binning and affinity determination.
? Support mAb humanization and optimization efforts.
? Perform monoclonal antibody developability assessment.
? Steer both internal as well as external (CRO) research efforts.
? Inform the project teams about generated data, progress and timelines in a
timely and clear and concise fashion

Qualifications
? PhD in biological engineering, biochemistry, molecular biology, or relevant
biological science with 5+ years of experience in the biotechnology and/or
pharmaceutical industry, developing therapeutic antibodies.
? Thorough understanding of the large molecule drug discovery process.
Knowledge of and experience with all aspects of mAb development are
desirable.
? Experienced in the characterization, analysis and development of therapeutics
proteins.
Expertise in protein analytical methods such as SPR/BLI-based techniques.
? Experience with the use of chromatographic methodologies (SEC, CIC, HIC) and
mass spectrometry-based techniques (peptide mapping)
Experience with outsourcing of research activities to contract research
organizations (CROs)
? Be a self-motivated, well-organized individual, capable of working independently
as well as in a collaborative/ group environment.
? Possess strong oral and written communication skills.

四川汇宇制药股份有限公司 企业介绍

    四川汇宇制药股份有限公司生产基地位于四川省内江经济技术开发区内，占地面积10万平方米,项目总投资10亿元人民币，致力于高端抗肿瘤药物的研发，生产和销售。公司在四川成都双流区“天府国际生物城”设立全球创新药研发中心，将打造抗体抗癌创新药物研发总部及产业化基地，建设包括从事靶向抗肿瘤小分子化学药和大分子生物药研发、中试及产业化的研发中心，占地面积60亩，规划建筑面积88000平方米，可容纳1500名研发人员，计划在2022年建成运行。
    公司以科技创新为导向的发展理念，不断完善小分子化学药物和单克隆抗体生物药物两个技术平台，开发抗肿瘤领域的创新药物，公司一期项目可年产3000万瓶抗癌针剂，实现年产值25亿元人民币。公司的抗癌针剂于2014年通过英国GMP认证，并于同年顺利通过中国GMP认证。2015年7月公司获得欧盟药品放行资质，公司生产的抗癌针剂已经在伊丽莎白女王医院、皇家伦敦医院和剑桥大学附属医院等1200多家欧盟医院作为一线抗癌药物大规模使用。
    公司在美国、英国、法国、澳大利亚、加拿大、中国香港等全球80多个国家和地区建立了销售渠道并启动了当地的药品注册工作，已逐步建立并完善遍布全球的销售网络。同时以致力于改善人类健康为崇高宗旨，以‘关爱生命，追求卓越，简单诚信’为价值导向， 力争把公司打造成一家受人尊敬的国际化制药企业。