上海 [切换城市] 上海招聘上海科研人员招聘上海科研管理人员招聘

Investigator, Developmental Biology

CNIBR-诺华(中国)生物医学研究有限公司

  • 公司性质:外资(非欧美)
  • 公司行业:制药/生物工程

职位信息

  • 发布日期:2013-11-06
  • 工作地点:上海
  • 招聘人数:1
  • 工作经验:三年以上
  • 学历要求:博士
  • 语言要求:英语熟练
  • 职位类别:医药技术研发管理人员  科研管理人员

职位描述

Job Purpose China NIBR based in Shanghai is dedicated to the research and development of products addressing diseases prevalent to China, and providing innovation in the understanding and curing of Epigenetic causes of diseases.
Cell fate specification and differentiation of stem cells into distinct cellular lineages during mouse embryogenesis are tightly regulated genetically and epigenetically, particularly via the interplay between key development regulators and various epigenetic modulations. Such interaction and similar mechanisms are also manifested during regeneration and aging processes. Epigenetic dysregulation will cause abnormal embryonic development and various human diseases. To aid target discovery and mechanistic understanding of regeneration, we are inviting applications for an Investigator position in the regenerative medicine research group. The successful candidate will be part of the developmental biology core, focusing on novel target discovery and disease modeling for regenerative medicine. He/She will be responsible for elucidating the roles of key epigenetic regulators during development and regeneration by using combinatory mouse genetics and epigenomic profiling approaches. The successful candidate will also participate in multi- disciplinary drug discovery and development team to support target discovery in disease areas of focus.
Minimum requirements
? Ph.D. in Developmental Biology, Cell Biology or related fields, minimal three years postdoc training
? Hands-on experience with mouse embryology, histology or pathology analysis; familiar with key developmental pathways such as Wnt, BMP, Notch etc.
? Deep understanding of epigenetics and proficient in research technologies such as ChIP-Seq, and DNA methylation analysis are required. .
? Highly self-motivated and highly collaborative team worker is essential. Previously industrial experience is preferable.

公司介绍

诺华(Novartis AG)是全球医药保健行业的领导者。其核心业务涉及专利药,非专利药,眼睛护理,消费者保健和动物保健等领域。诺华公司总部设在瑞士巴塞尔,业务遍及全球140多个国家和地区。

诺华(中国)生物医学研究有限公司是诺华全球研发组织――诺华生物医学研究所(NIBR)的第八个研究基地。我们位于中国上海市张江高科技园区,将成为诺华在亚洲的主要研究中心,以及除在欧美的研究中心外的最主要的研究中心。我们的研究和探索开发活动的重点是发现并开发创新疗法,用于治疗在亚洲远未达到医药需求的疾病。我们与从不同之处在于将专注现代药物的发现和开发方法的研究。最初阶段,研发工作将专注在引起中国地方性癌症的感染原因。我们还将开展临床试验,进行安全性研究,生物标志物和检测分析,表达谱、生物分析以及转化医学的研究。

随着公司业务的迅速扩展,我们热忱欢迎您的加入。同时我们将提供具有竞争力的薪酬福利待遇以及良好的培训发展机会。