上海招聘

  

1. Lead/contribute to establishing CLD platform including expression hosts, vector systems, and screening technologies

2. Lead/conduct plasmid/expression vector construction and optimization, and CHO host cell line engineering

3. Lead/conduct CHO cell line generation in accordance of regulatory guidance

4. Manage/coordinate CLD resources and strategic planning to support early and late stage projects.

5. Design and conduct experiments, collect and analyze data, write development reports

6. Drive innovation through deep understanding of new technologies and methods in cell line development

7. Coordinate and collaborate with Discovery and other CMC functions and develop strategies to meet project as well as corporate timelines

8. Contribute to the IND filings

                

Requirements:

  

1. BS/BA or MS or PhD in Cell Biology, Molecular Biology, Biochemistry or related field. Number of years of industry experience commensurate with job titles

  

2. Hands-on experience in mammalian cell culture and molecular cloning techniques

  

3. Experience in expression of monoclonal antibodies, bispecific antibodies, Fc-fusions and other therapeutic proteins

  

4. Versatile in techniques including DNA/RNA isolation, molecular cloning, PCR, protein expression and purification

  

5. Extensive knowledge and experience in IND filing

  

6. Extensive knowledge and skills in molecular and cellular biology. Protein/cell engineering preferred

  

7. Strong communication and problem-solving skills

  

8. Strong working knowledge/understanding of CHO expression systems

  

9. Ability to work independently and multitask in a fast-paced environment

  

10. Responsible, organized and disciplined record keeping

  

11 Self-motivated, collaborative, and effective communication skill

  

和铂医药是一家专注于肿瘤免疫领域创新药物研究与开发的全球化运营生物医药公司。公司将运用其拥有的全部自主知识产权的全人源单抗的转基因鼠系列核心技术平台，建立下一代治疗性肿瘤抗体药物产品管线,并将围绕Harbour的两大平台拓展合作与授权业务。公司总部及研发基地位于中国上海，另外在美国马塞诸塞州剑桥设立商业运营中心，在荷兰鹿特丹设立抗体研发平台创新中心，在波士顿地区设立了创新中心包括实验室和研发团队，也将在江苏昆山设立研发基地。公司拥有资深管理团队以及丰富的药物研究与开发经验。和铂医药要为满足中国及全球病人的需求而不断努力，依托拥有自主知识产权的核心技术平台,创建一个在肿瘤治疗领域有科学与技术领导力的国际性生物医药公司。同时, 在药物研发领域建立以技术平台为基础的对外合作，整合新的技术，推动中国整个抗体研发产业的进步。

Company Overview
Harbour BioMed is a global biotechnology company discovering and developing innovative therapeutics for cancer with a focus on immuno-oncology and autoimmunity/inflammation. The company's discovery and development programs are centered around its two patented transgenic mouse platforms for human antibody discovery.
The company is building its proprietary pipeline internally, through collaborations with co-development partners, as well as through selective preclinical and clinical stage asset acquisitions. Harbour BioMed also licenses the platforms to companies and academic institutions through its Harbour Antibodies subsidiary.
Harbour BioMed has headquarters and an R&D site in Shanghai, business operations in Cambridge, MA, and antibody platform development in Rotterdam, The Netherlands.
The company has an innovation center including research lab and a development team in Boston. Also, we are expanding to Kunshan site in Jiangsu for our R&D operation.