Research Associate in Molecular Biology, BRCMB0136(职位编号:5223BR)
诺和诺德(中国)制药有限公司
- 公司规模:500-1000人
- 公司性质:外资(欧美)
- 公司行业:制药/生物工程
职位信息
- 发布日期:2012-09-07
- 工作地点:北京
- 招聘人数:若干
- 工作经验:二年以上
- 学历要求:本科
- 语言要求:英语熟练
- 职位类别:生物工程/生物制药 医药技术研发人员
职位描述
Biopharm Research China (BRC) is one of the research units in Novo Nordisk China R&D and a fully integrated part of the Biopharmaceuticals Research Unit (BRU) in Denmark. We are committed to developing innovative biologics to improve the lives of people with haemophilia, growth disorders and autoimmune inflammatory diseases. By leveraging our core competences in protein and antibody engineering & production, we support Novo Nordisk pipeline projects in turning naturally occurring proteins into valuable pharmaceuticals and contribute to the identification of new molecular targets for the treatment of diseases. Currently BRC has three research departments.
Molecular Biology Department
We develop and master state-of-the-art bacterial and mammalian expression systems for the production of recombinant proteins in support of our portfolio. We are also engaged in the development of advanced technology platforms for antibody engineering including antibody humanization, phage display, E. coli display and associated high throughput screening capacity. We are constantly striving on building competences in the field of molecular antibody technology to modify, engineer and express proteins with desirable profiles.
Protein Chemistry Department
We are passionate and rigorous about proteins. We develop and implement advanced protein purification and characterization technologies for production of high quality bacterial/mammalian expressed recombinant proteins and in-house generated antibodies. Guided by protein structure determination and modern bioinformatics tools, we design proteins with improved biophysical and biological profiles. Together with our globalized R&D teams, we are actively involved in formulation and promotion of new ideas and innovations.
Cell Biology Department
We are responsible for the establishment of immunotechnology platforms and expertise in in vitro mammalian cell biology in support of our portfolio. We focus on assay antibody generation and production using hybridoma technology as well as cell based functional assays. We are dedicated in building competences in disease biology and understanding within our therapy areas. In addition, we are very engaged in presenting new potential drug targets to secure expansion and quality in our international project portfolio.
Our ability to excel depends on the integrity, knowledge, dedication, and teamwork from each employee. Working with us, you will have the opportunity to collaborate with talented colleagues in an international environment, while developing and expanding your career. Welcome to BRC!
Job Description:
We are looking for a research associate with experience in molecular biology, protein expression and characterization. The successful candidate will work within a team on the development of therapeutic antibodies for inflammation.
Responsibility included but not limited to:
1. Design primers for DNA cloning and mutagenesis.
2. Perform DNA cloning and mutagenesis for various proteins.
3. Express proteins with E.coli and mammalian cells.
4. Analyze protein binding by: ELISA, FACS, Immunoblotting and other immunoassays as needed.
5. Analyze data from experiments, write summaries, and prepare presentations, etc.
Qualification:
1. BS or MS degree in molecular biology-related biological field
2. 2+ years for BS of laboratory research experience 3. Expertise in molecular cloning, cell culture and protein expression is a must
4. Experience with large scale mammalian cell culture, or high throughput liquid handling, or phage display technology, or antibody engineering is a strong plus.
5. Good verbal and written skills in English.
6. Strong organization and communication skill, and a desire to work cooperatively in a team environment.
Molecular Biology Department
We develop and master state-of-the-art bacterial and mammalian expression systems for the production of recombinant proteins in support of our portfolio. We are also engaged in the development of advanced technology platforms for antibody engineering including antibody humanization, phage display, E. coli display and associated high throughput screening capacity. We are constantly striving on building competences in the field of molecular antibody technology to modify, engineer and express proteins with desirable profiles.
Protein Chemistry Department
We are passionate and rigorous about proteins. We develop and implement advanced protein purification and characterization technologies for production of high quality bacterial/mammalian expressed recombinant proteins and in-house generated antibodies. Guided by protein structure determination and modern bioinformatics tools, we design proteins with improved biophysical and biological profiles. Together with our globalized R&D teams, we are actively involved in formulation and promotion of new ideas and innovations.
Cell Biology Department
We are responsible for the establishment of immunotechnology platforms and expertise in in vitro mammalian cell biology in support of our portfolio. We focus on assay antibody generation and production using hybridoma technology as well as cell based functional assays. We are dedicated in building competences in disease biology and understanding within our therapy areas. In addition, we are very engaged in presenting new potential drug targets to secure expansion and quality in our international project portfolio.
Our ability to excel depends on the integrity, knowledge, dedication, and teamwork from each employee. Working with us, you will have the opportunity to collaborate with talented colleagues in an international environment, while developing and expanding your career. Welcome to BRC!
Job Description:
We are looking for a research associate with experience in molecular biology, protein expression and characterization. The successful candidate will work within a team on the development of therapeutic antibodies for inflammation.
Responsibility included but not limited to:
1. Design primers for DNA cloning and mutagenesis.
2. Perform DNA cloning and mutagenesis for various proteins.
3. Express proteins with E.coli and mammalian cells.
4. Analyze protein binding by: ELISA, FACS, Immunoblotting and other immunoassays as needed.
5. Analyze data from experiments, write summaries, and prepare presentations, etc.
Qualification:
1. BS or MS degree in molecular biology-related biological field
2. 2+ years for BS of laboratory research experience 3. Expertise in molecular cloning, cell culture and protein expression is a must
4. Experience with large scale mammalian cell culture, or high throughput liquid handling, or phage display technology, or antibody engineering is a strong plus.
5. Good verbal and written skills in English.
6. Strong organization and communication skill, and a desire to work cooperatively in a team environment.
公司介绍
诺和诺德是世界领先的生物制药公司,在用于糖尿病治疗的胰岛素开发和生产方面居世界领先地位。诺和诺德总部位于丹麦首都哥本哈根,员工总数30000人,分布于79个国家,产品销售遍布180个国家。在欧美均建有生产厂。
诺和诺德的产品60年代初就已进入中国市场。1994年初,诺和诺德董事会通过了在中国实施战略投资的计划,在北京建立诺和诺德(中国)制药有限公司总部和生物技术研究发展中心,在天津兴建现代化生产工厂,并在全国30多个城市建立了完善的营销体系。欲了解详情,请访问诺和诺德中国网站:www.novonordisk.com.cn
为配合公司在中国业务的迅速发展,现诚聘。
诺和诺德将为您提供具有竞争力的福利、完善的个人发展与培训机会,使您在国际化的管理与富有挑战性的工作环境中不断地进步与自我实现!应聘者请将个人简历、期望薪水、身份证、学历证明复印件于10日内寄至本公司。
请在信封上注明应聘职位。
诺和诺德的产品60年代初就已进入中国市场。1994年初,诺和诺德董事会通过了在中国实施战略投资的计划,在北京建立诺和诺德(中国)制药有限公司总部和生物技术研究发展中心,在天津兴建现代化生产工厂,并在全国30多个城市建立了完善的营销体系。欲了解详情,请访问诺和诺德中国网站:www.novonordisk.com.cn
为配合公司在中国业务的迅速发展,现诚聘。
诺和诺德将为您提供具有竞争力的福利、完善的个人发展与培训机会,使您在国际化的管理与富有挑战性的工作环境中不断地进步与自我实现!应聘者请将个人简历、期望薪水、身份证、学历证明复印件于10日内寄至本公司。
请在信封上注明应聘职位。
联系方式
- 公司网站:http://www.novonordisk.com.cn
- 公司地址:北京市朝阳区广顺南大街8号利星行中心3号楼4,5层 (邮编:100102)
- 邮政编码:100020
- 电话:18701492989