南京招聘

The successful applicant for this position will be joining Cell Culture Development team within Clinical Development in Lonza Guangzhou, China. The Clinical Development group are responsible for the development and characterization of manufacturing processes used for the production of novel therapeutic recombinant proteins for Lonza’s global client base. The purpose of this role is to execute cell line and process development activities and to provide technical expertise to support troubleshooting activities at both laboratory and manufacturing scale.

 

Duties and Responsibilities include:

• To perform hands-on laboratory work in the cell line and upstream process development team contributing to the development of processes and creation of cell lines suitable for technology transfer to the Current Good Manufacture Practices (cGMP) manufacturing teams. An understanding of Current Good Manufacture Practices (cGMP) manufacturing facility constraints and their impact on development activities will be developed.

• Contribute to customer projects by generating and interpreting scientific data from experimental work.

• Interpret analytical data provided by the analytical team to define subsequent steps.

• Deliver high quality communication to ensure an outstanding customer experience (written reports, presentations, teleconferences, face to face meetings).

• Working as part of a site and global project team, co-ordinate multiple projects (if at senior level) and ensure timely delivery of project workstages.

• Cell culture processes include; Cell Line Development (routine cell culture, transfection, Fluorescence Activating Cell Sorter, cell imaging); Process Development (ambr15 miniaturized bioreactors, 10L laboratory scale bioreactors, single use bioreactors)

• General laboratory support including housekeeping, equipment calibration and maintenance, inventory of supplies, etc.

• Documentation of results in accordance with Lonza policies and current Good Manufacturing Practices (cGMP).

• Review of data (if at senior level) generated by others highlighting any unusual or atypical results/procedures.

• May mentor junior members (if at a senior level) to assist in their development, providing a transfer of knowledge and hands-on technical training.

• The initial phase of this position will be involved in the establishment of the facility (including but not limited to equipment and inventory purchase, equipment qualification runs, facility design and set up).

   

  General

• To work to the highest scientific and quality standards under the direction of the Line Manager.

• To communicate project updates to internal and external customers.

• To contribute to the efficient running of the department including instigating and delivering operational efficiency projects.

• Lead improvements in scientific practice and identify error traps within the laboratory and within processes to improve standards.

• Contribute to departmental safety and training programmes as required.

• Dependent on scale of project, supervision of project teams may be required (if at a senior level).

• The role will require weekend and public holiday working on a rota based system.

• Exposure to cell culture processes executed in a Current Good Manufacture Practices facility would be considered advantageous.

• Knowledge and demonstrated application of the relevant International Conference on Harmonization of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH) guidelines in the area of upstream process development.

• Well-organised – must be able to co-ordinate multiple tasks

• Flexible – is willing to undertake a range of tasks for the efficient running of the department.  Is willing to work the hours required for the successful completion of department deliverables

   

   

Job Requirement:

• Degree/ Doctor of Philosophy in a relevant Science field or Equivalent

• Practical laboratory experience in cell culture is required

• The final role offered will be commensurate with the candidate’s experience.

• Understanding of theory and application of mammalian cell culture.

• Understanding of Current Good Manufacture Practices regulations will be advantageous

• Good problem solving and analytical skills.

• Good communication skills (verbal and written).

• Good teamworking skills.

• Fluency in written and spoken English will be advantageous

   

What we offer:

At Lonza, we invest in great people. We encourage our employees to challenge themselves, and we offer an environment that fosters creativity and success, where you can develop your skills and knowledge by working in teams of highly collaborative experts in a rewarding and dynamic atmosphere. With headquarters in Basel, Switzerland, we operate production, Research and Development and business sites around the world, including Europe, North America and Asia.

 

Lonza is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, colour, national origin, sex, sexual orientation, gender identity, age, status as a qualified individual with disability, protected veteran status, or any other characteristic protected by law.

关于龙沙
在龙沙，我们将技术创新与卓越生产及工艺完美结合，助力我们的客户在保健、防腐与保护领域实现他们的研发成果。

我们是全球制药、生物技术与特殊成分市场的优秀合作伙伴。 我们致力于疾病预防，并通过助力客户推出创新药物用以辅助治疗或治愈一系列的疾病，促进我们的世界更健康。同时，我们也提供广泛的微生物控制解决方案，共同营造和维护健康的环境。

1897年，龙沙诞生于瑞士的阿尔卑斯山脉地区，迄今拥有 120 个生产基地和办事处，遍布全球超过35个国家。 我们拥有约15,500名全职员工，由他们组成的高效团队及每一名员工都为我们的业务和所在地区及国家做出意义非凡的改变。2019 年，公司销售额达59亿瑞士法郎，核心业务的息税折旧摊销前利润（EBITDA）达16亿瑞士法郎。更多详情，请访问 *************。


About Lonza
At Lonza, we combine technological innovation with world class manufacturing and process excellence. Together, these enable our customers to deliver their discoveries in the healthcare, preservation, and protection sectors.
We are a preferred global partner to the pharmaceutical, biotech and specialty ingredients markets. We work to prevent illness and promote a healthier world by enabling our customers to deliver innovative medicines that help treat or even cure a wide range of diseases. We also offer a broad range of microbial control solutions, which help to create and maintain a healthy environment.
Founded in 1897 in the Swiss Alps, Lonza today operates in 120 sites and offices in more than 35 countries. With approximately 15,500 full-time employees, we are built from high-performing teams and of individual employees who make a meaningful difference to our own business, as well as the communities in which we operate. The company generated sales of CHF 5.9 billion in 2019 with a CORE EBITDA of CHF 1.6 billion. Find out more at ************* and follow us on Twitter @LonzaGroup or Facebook @LonzaGroupAG.