南昌招聘

Summary

The Computational Chemistry Group of Shanghai ChemPartner co. is seeking a Computational Chemist who can successfully work as part of a multifunctional team to discover and optimize small molecule drug leads, to successfully carry out projects/services for our international and domestic clients. Hands-on experience in one or more of the following areas is required: structure-based drug design, docking, pharmacophore modeling, QSAR, 3D-QSAR, 3D database searching, shape based searching, combinatorial library design, target focused library construction, cheminformatics, lead optimization and homology modeling. Familiarity with state-of-the-art computational techniques and software, such as Schr？dinger, Sybyl, MOE, Discovery Studio, Gaussian and Pipeline Pilot is required.

Qualifications

• The successful candidate will have a master or Ph.D. degree in computational chemistry, or the same degree in organic chemistry with more than two years of experience in computational chemistry and structure/ligand-based drug design.
• Industry experience is preferred. Strong commitment to business ethics is essential.
• A track record of technical excellence, effective communication and teamwork, is required for this position.
• Proficiency in English writing and speaking is preferred. Skillful in Linux or UNIX operating system is a plus.

Duties and Responsibilities

• Provide computational/modeling support to our client’s cross-functional drug discovery projects in advancing small-molecule drug discovery programs from target identification through lead optimization.
• Plan and execute computational chemistry strategy for integrated drug discovery service.
• Work closely with medicinal chemists and project teams in the design and optimization of compounds with improved potency, selectivity, functional activity on their protein target, together with improved ADME properties, using computational technologies as necessary.
• Analyze and interpret experimental data; perform SAR analysis and provide ideas to improve the next round of lead compounds.

上海睿智化学研究有限公司成立于2002年，是一家世界领先的科研外包服务机构(CRO)，秉承着创新驱动、客户至上的服务理念，致力于为全球制药公司和生物技术公司提供全面且高品质的新药研发服务。
公司业务涵盖了抗体早期研发、小分子早期研发、药理药效、药代药动及早期毒理、生物药CMC、化药CMC、临床样品生产等新药研发各环节，为客户提供整合一体化的新药研发外包服务，已经服务过的国内外制药企业和生物医药技术公司1000余家，其中包括全球排名前20位的医药和生物技术企业。

公司在全球设立了6个办事处，专职研发人员2000人，海归科学家150人，拥有大规模最先进的科研、办公设施、实验动物设施、cGMP级别的公斤级实验室以及医药中间体生产设施。公司通过坐落于张江、奉贤、启东、成都和南旧金山五个重要研发基地持续不断为来自全球范围内客户长期提供优质的服务。