多肽化学高级研究员
恒瑞医药-江苏科信医药销售有限公司
- 公司规模:10000人以上
- 公司性质:上市公司
- 公司行业:制药/生物工程
职位信息
- 发布日期:2020-11-09
- 工作地点:北京
- 招聘人数:若干人
- 工作经验:无需经验
- 学历要求:博士
- 职位月薪:2-2.5万/月
- 职位类别:医药技术研发人员
职位描述
工作内容:
1.对新型多肽类药物分子进行分子设计,合成和纯化并评估其体外/体内药效特性;
2.设计并执行新型生物药候选分子的合成和纯化,包括多肽合成及蛋白/抗体选择性化学修饰;
3.用UPLC, LC-MS等表征手段对合成肽/蛋白类分子进行表征和结构分析;
4.与公司内部其它部门同事合作协同推进多肽类早期药物研发项目;
5.了解并应用多肽药物化学领域最新科研进展和技术手段。
Responsibility:
1.Design, synthesize and perform purification of novel peptide-based molecules to achieve desired pharmacological properties;
2.Plan and execute laboratory experiment to generate novel biopharmaceuticals including peptide synthesis and protein chemical modification;
3.Characterize peptide or protein-based biopharmaceuticals using UPLC, LC-MS and other relevant biophysical techniques;
4.Collaborate with colleagues at the multidisciplinary project team to advance early stage drug discovery project;
5.Keep up with recent literature and other technological advance in the peptide medicinal chemistry field.
基本要求:
1.在有机化学/药物化学/多肽化学领域具有博士学位并具有2年博士后/制药企业相关研发经验;
2.具有多肽药物化学及多肽结构-活性研究的相关经验;
3.具有一定小分子全合成经验者优选考虑;
4.熟悉并掌握常见的多肽/蛋白结构分析和表征手段,包括但不局限于HPLC, UPLC, SEC和LC-MS;
5.具有在多领域交叉学科药物发现团队工作的经验,能区分工作优先级和主次顺序;
6.具有良好的沟通能力和团队精神。
Qualification:
1.Ph.D degree in peptide chemistry/organic chemistry with 2 years of relevant experience in an industrial or postdoctoral setting;
2.Prior experience in the design and synthesis of peptide libraries and performing peptide structure-activity relationship study;
3.Prior experience in small molecule organic synthesis is an advantage;
4.Must be familiarized with standard peptide characterization techniques including but not limited to: HPLC, UPLC, SEC and LC-MS;
5.Must be able to work on project of multidisciplinary nature, with strong work ethics and ambition to learn and take responsibility; 6.Strong communication and teamwork skills.
职能类别:医药技术研发人员
公司介绍
江苏科信医药销售有限公司是恒瑞医药的销售公司,承担着恒瑞医药抗肿瘤药、造影剂、输液、内分泌、心血管、医疗器械等产品的销售和市场推广职能。
联系方式
- Email:1410@163.com
- 公司地址:上海市浦东新区海科路1288号 (邮编:200120)
- 电话:15167061340