北京招聘

Novo Nordisk is a focused healthcare company and a world leader in diabetes care. Novo Nordisk Research Centre China (NNRCC) is an integrated part of Novo Nordisk R&D organization. Novo Nordisk wants to conduct diabetes research activities in China and expand its network to the scientific community. For these purposes, a new position is open for a highly qualified and motivated scientist within molecular biology who plans to advance a career in China.

Department of Diabetes Protein Engineering is part of Novo Nordisk Research Centre China and located in Beijing. The department is responsible for support of diabetes and obesity research projects in the discovery phase. Currently, the department consist of 8 scientists, 13 research assistants and a department director. We are a highly motivated and productive team with high standards for our deliveries into the projects and an increasing focus on flexible processes in our daily work. We work with state-of-the-art facilities and equipment and value a high team spirit, good communication and dynamic collaboration between both scientists and technicians. The department is expected to grow over the next years, which leads to excellent opportunities for individual development for our scientists.

Challenges
You will be involved in cross-functional project teams with colleagues from many different scientific backgrounds both in China and at our head quarters in Denmark. You will contribute to several early stage projects with responsibility for designing expression systems and generating recombinant proteins preferentially from E. coli, but some experience within mammalian expression is also considered valuable. You will also be responsible for process development and handing over of the E.coli process to CMC settings including documentation in relation to the transfer.

You will be reporting directly to the department director and your main internal contacts will be scientist colleagues, technicians and project members and managers both in Beijing and in Denmark. Furthermore, developing and maintaining a strong external network is also going to be an important part of your work.
You will be part of a team in a highly dynamic and challenging environment within the Diabetes Research Unit.
Your tasks will include, but not be limited to:
·Developing effective microbial host/vector systems using recombinant DNA technology, including: identification of expression limiting steps, protein secretion (i.e. periplasmic or extracellular expression), posttranslational issues, physiological manipulation of host strains, in-vivo protein misfolding (inclusion body expression), fusion-protein technology, molecular manipulation of proteins, pathway knockouts, pathway constructions,
·Analyze data from experiments, write summaries, and prepare presentations
·Manage projects in a diverse team environment
Furthermore, you will be expected to lead the implementation of new technologies within protein and peptide expression as needed.

Qualifications
·You hold a Ph.D. in molecular biology, biochemistry, genetics or related discipline with additional postdoctoral training or similar experience.
·You must demonstrate strong experience in at least one of the following areas: metabolic engineering, protein engineering, protein expression in microorganisms (preferably E.coli), protein expression with unnatural amino acids, genetic manipulation of bacteria, enzyme evolution, microbial physiology.
·You have an excellent track record of original research as well as hands-on experience with state-of-the art molecular biological techniques.
·Experience from a biotech/pharmaceutical R&D setting taking a therapeutic protein all the way from early expression in E.coli to handing over to CMC setting is considered an advantage.
·You are flexible, open to new ideas, ambitious, innovative; result oriented and have a good sense of humour.
·You have authority and thrive in an environment with individual responsibility and a high degree of personal impact in the projects but at the same time you are good at collaborating in teams.
·You are good at communicating, able to meet deadlines and keep an overview.
·You are fluent in English.

Title and compensation will be commensurate with the applicant’s qualifications and based on benchmark in China.

　　诺和诺德是世界领先的生物制药公司，在用于糖尿病治疗的胰岛素开发和生产方面居世界领先地位。诺和诺德总部位于丹麦首都哥本哈根，员工总数30000人，分布于79个国家，产品销售遍布180个国家。在欧美均建有生产厂。
　　诺和诺德的产品60年代初就已进入中国市场。1994年初，诺和诺德董事会通过了在中国实施战略投资的计划，在北京建立诺和诺德（中国）制药有限公司总部和生物技术研究发展中心，在天津兴建现代化生产工厂，并在全国30多个城市建立了完善的营销体系。欲了解详情，请访问诺和诺德中国网站：www.novonordisk.com.cn

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