北京招聘

PURPOSE OF THE ROLE

Within the Biodevelopment Process Development group, will execute projects including developing, validating and transferring chromatographic methods for biotech molecules. Execute client project according to budget and timelines given to the project team.

Develop, validate and transfer robust analytical methods required for successful drug development and manufacturing.

Support follow-up and throubleshooting on analytical methods.

Support process and pharmaceutical development with chromatographic methods, technical expertise and solutions.

Compile and analyze experimental data to generate process knowledge and decide on next steps

Write development and validation reports and ensure their timely delivery

Prepare and present project updates to global project team and to upper management

 

KEY RESPONSIBILITIES

• Good knowledge on biotech processes development and protein purification.

• Consolidated knowledge on protein chemistry and direct experience on protein analysis by chromatographic, electrophoretic, spectroscopic and mass spectrometry techniques

• Excellent knowledge of analytical development of chromatographic methods, validation, tech transfer  and applied statistics;

• To conduct sample testing for lot release, in-process, stability and R&D samples

• Knowledge of common and specific software in use in analytical labs;

• To ensure compliance to regulatory requirement, including instrument maintenance, personnel training, document drafting, review and archiving

• Responsible for biophysical characterization of proteins:-

  • Perform analyses including but not limited to SDS-PAGE, SE-HPLC, LAL, host cell-DNA, host cell protein, as necessary

  • To develop, validate and transfer robust analytical methods required for successful drug development and manufacturing.

  • To support follow-up and troubleshooting on analytical method 

 

EDUCATION AND EXPERIENCE

 

• MS or above in Biochemistry/Biotechnology, Cell Biology, Immunology or related

• Experienced in protein purification via affinity, hydrophobic interaction (HIC), ion exchange (IEX), size exclusion (SEC) and mixed-mode chromatography

• Knowledge and skills in biochemical characterization of proteins including analytical and biophysical techniques.  Experience with protein formulation strategies is highly desirable.

• Solid working knowledge of DOE. Ability to critically analyze data using statistical tools and to compile technical reports

• Good presentation and communication skills

• Results-oriented with ability to work and deliver under pressure

• Excellent English (written, oral)

默克是一家全球领先的科技公司，专注于医药健康、生命科学和电子科技三大领域。全球约有58,000名员工服务于默克，通过创造更加愉悦和可持续性的生活方式，为数百万人的生活带来积极的影响。从先进的基因编辑技术和发现治疗具有挑战性疾病的独特方法，到实现设备的智能化——默克无处不在。2020年，默克在66个国家的总销售额达175亿欧元。
科学探索和负责任的企业精神一直是默克科技进步的关键，也是默克自1668年以来永葆活力的秘诀。默克家族作为公司的创始者至今仍持有默克大部分的股份，我们在全球都叫“默克”，仅美国和加拿大例外。默克的三大领域：医药健康、生命科学及电子科技在这两个国家分别称之为“EMD Serono”、“MilliporeSigma”和“EMD Electronics”。
关于默克中国
默克在中国已经有88年发展历史，***家在华的分公司***于1933年在上海成立。中国是默克在全球最为重要的战略国家之一，并且已成为默克的一个全球创新中心。近几年，默克的医药健康和生命科学业务在南通以及电子科技业务在上海的投资分别达到1.7亿欧元、8000万欧元和4400万欧元。此外，默克还在北京设立了全球生物制药研发中心，在上海设有显示材料研发中国中心、外观科技应用技术中国中心、OLED技术中国中心、生命科学实验室以及亚太区BioReliance？ End-to-End生物工艺开发中心，在苏州设有光刻材料研发中国中心。2018年，默克宣布在上海和广东设立中国创新中心。
目前默克中国有超过4,200名员工，在北京、上海、香港、无锡、苏州和南通有21个注册公司。每天，我们都在致力于提供高品质和创新的产品和服务，对人们的生活产生积极的影响。
每天，默克中国超过4,200名的员工都在致力于提供高品质和创新的产品和服务，对人们的生活产生积极的影响。